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Endocrine system

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15 min
Topic
Biology
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C-class
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5.1k in 14 days
Last edited
16 Oct 2026
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  1. Endocrine system
Endocrine system
Hormone-producing glands of a body
Latinsystema endocrinum
MeSHD004703
FMA9668

The endocrine system1 is a messenger system in an organism comprising feedback loops of hormones that are released by internal glands directly into the circulatory system and that target and regulate distant organs. In vertebrates, the hypothalamus is the neural control center for all endocrine systems.

In humans, the major are the , , , , and , and the (male) and (female) . The , , and also function as endocrine glands, among other functions. (The hypothalamus and pituitary glands are organs of the . One of the most important functions of the hypothalamus—it is located in the adjacent to the pituitary gland—is to link the endocrine system to the via the pituitary gland.) Other organs, such as the , also have roles within the endocrine system by secreting certain hormones. The study of the endocrine system and its disorders is known as . The secretes , the secretes , the secretes , the testis secretes , and the secrete and .

endocrine glands
thyroid
parathyroid
pituitary
pineal
adrenal glands
testis
ovaries
hypothalamus
pancreas
thymus
neuroendocrine system
brain
nervous system
kidneys
endocrinology
thyroid
thyroxine
pituitary
growth hormone
pineal
melatonin
testosterone
ovaries
estrogen
progesterone
2

Glands that signal each other in sequence are often referred to as an axis, such as the hypothalamic–pituitary–adrenal axis. In addition to the specialized endocrine organs mentioned above, many other organs that are part of other body systems have secondary endocrine functions, including bone, kidneys, liver, heart and gonads. For example, the kidney secretes the endocrine hormone erythropoietin. Hormones can be amino acid complexes, steroids, eicosanoids, leukotrienes, or prostaglandins.3

The endocrine system is contrasted both to exocrine glands, which secrete hormones to the outside of the body, and to the system known as paracrine signalling between cells over a relatively short distance. Endocrine glands have no ducts, are vascular, and commonly have intracellular vacuoles or granules that store their hormones. In contrast, exocrine glands, such as salivary glands, mammary glands, and submucosal glands within the gastrointestinal tract, tend to be much less vascular and have ducts or a hollow lumen. Endocrinology is a branch of internal medicine.3

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General
  • Recent changes
  • Related articles
  • Random discovery
This article
Reading time
15 min
Topic
Biology
Quality
C-class
Views
5.1k in 14 days
Last edited
16 Oct 2026
Print/export
  • Printable version
In other projects
  • Wikidata item
Last edited
16 Oct 2026